Algorithm Research & Explore
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App. Res. of Comp. Printed Article
Vol. 38, 2021 No. 3
777-781

Application of DNA origami in 0-1 backpack problem

Yang Xinmu1a
Yang Jing1a,2
Yin Zhixiang3
Tang Zhen1a
Cui Jianzhong1b,4
1. a. School of Mathematics & Big Data, b. School of Electrical & Information Engineering, Anhui University of Science & Technology, Huai-nan Anhui 232001, China
2. Faculty of Education, The University of Hong Kong, Hong Kong 999077, China
3. School of Mathematics, Physics & Statistics, Shanghai University of Engineering Science, Shanghai 201620, China
4. Dept. of Computer Science, Huainan Union University, Huainan Anhui 232001, China
DOI: 10.19734/j.issn.1001-3695.2020.01.0005

Abstract

DNA origami is widely used in DNA computing by its programmability and nano-addressability. This paper used DNA origami and hybrid chain reaction to construct a model for solving the 0-1 knapsack problem. Taking the 0-1 knapsack problem with 4 variables as an example, firstly, it anchored nine hairpin structures and one molecular beacon to the DNA origami substrate and added a sufficient amount of auxiliary chains. Secondly, it added different trigger chains could trigger hybrid chain reaction on different paths so as to get all possible solutions. Finally, it used the number of fluorescent signals to find feasible and optimal solutions. The model is not affected by too large or too small weights, and can scale the weights equally on the origami substrate. The simulation is carried out by Visual DSD and the result shows that this model has good feasibility.

Foundation Support

国家自然科学基金资助项目(61702008,61672001)
安徽省博士后基金资助项目(2019B331)
安徽省自然科学基金资助项目(1808085MF193)
2019年高校优秀青年骨干人才国外访问研修项目(gxgwfx2019015)
安徽高校自然科学研究项目(KJ2019A0538)

Publish Information

DOI: 10.19734/j.issn.1001-3695.2020.01.0005
Publish at: Application Research of Computers Printed Article, Vol. 38, 2021 No. 3
Section: Algorithm Research & Explore
Pages: 777-781
Serial Number: 1001-3695(2021)03-026-0777-05

Publish History

[2021-03-05] Printed Article

Cite This Article

杨新木, 杨静, 殷志祥, 等. DNA折纸术在0-1背包问题中的应用 [J]. 计算机应用研究, 2021, 38 (3): 777-781. (Yang Xinmu, Yang Jing, Yin Zhixiang, et al. Application of DNA origami in 0-1 backpack problem [J]. Application Research of Computers, 2021, 38 (3): 777-781. )

About the Journal

  • Application Research of Computers Monthly Journal
  • Journal ID ISSN 1001-3695
    CN  51-1196/TP

Application Research of Computers, founded in 1984, is an academic journal of computing technology sponsored by Sichuan Institute of Computer Sciences under the Science and Technology Department of Sichuan Province.

Aiming at the urgently needed cutting-edge technology in this discipline, Application Research of Computers reflects the mainstream technology, hot technology and the latest development trend of computer application research at home and abroad in a timely manner. The main contents of the journal include high-level academic papers in this discipline, the latest scientific research results and major application results. The contents of the columns involve new theories of computer discipline, basic computer theory, algorithm theory research, algorithm design and analysis, blockchain technology, system software and software engineering technology, pattern recognition and artificial intelligence, architecture, advanced computing, parallel processing, database technology, computer network and communication technology, information security technology, computer image graphics and its latest hot application technology.

Application Research of Computers has many high-level readers and authors, and its readers are mainly senior and middle-level researchers and engineers engaged in the field of computer science, as well as teachers and students majoring in computer science and related majors in colleges and universities. Over the years, the total citation frequency and Web download rate of Application Research of Computers have been ranked among the top of similar academic journals in this discipline, and the academic papers published are highly popular among the readers for their novelty, academics, foresight, orientation and practicality.

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