Research status and prospect of DNA-based logic computing models

Zhao Yunbin
Zhou Shihua
Key Laboratory of Advanced Design & Intelligent Computing of Ministry of Education, Dalian University, Dalian Liaoning 116622, China

Abstract

DNA computing has become a hot topic in current research due to its excellent computing performance, and DNA logic computing models is an important implementation tool for DNA computing system and computing implementation. Existing DNA logic computing models are classified according to application technology: DNA logic computing models based on strand displacement, DNA logic computing models based on nucleic acid enzymes, DNA logic computing models based on G-quadruplex, DNA logic computing models based on self-assembly, DNA logic computing models based on other molecular technologies and molecular materials. Firstly, this paper described the research background and research purposes of DNA logic computing and its applications in biomolecular detection, disease diagnosis, multi-factor analysis and bioimaging. Then, this paper sorted out the research history and current status of various types of DNA logic computing models, and analyzed the molecular manipulation techniques and molecular materials used in various logic computing models, as well as the advantages and disadvantages and application prospects. Finally, this paper summarized the current research hotspots and development prospects in the field of DNA logic computing, laying the foundation for a new calculation method for the future, and providing better services for information science, medical diagnosis and other fields.

Foundation Support

国家自然科学基金资助项目(61425002,61402067,61772100,61572093,61402066,61672121,61672051)
国家教育部“长江学者和创新团队”发展计划资助项目(IRT_15R07)
辽宁省创新团队支持计划资助项目(LT2015002)
辽宁省教育厅重点实验室基础研究项目(LZ2014049,LZ2015004)
辽宁省高校科学研究基金资助项目(L2015015)

Publish Information

DOI: 10.19734/j.issn.1001-3695.2018.07.0512
Publish at: Application Research of Computers Printed Article, Vol. 36, 2019 No. 11
Section: Survey
Pages: 3201-3209
Serial Number: 1001-3695(2019)11-001-3201-09

Publish History

[2019-11-05] Printed Article

Cite This Article

赵云彬, 周士华. DNA逻辑计算模型的研究现状与展望 [J]. 计算机应用研究, 2019, 36 (11): 3201-3209. (Zhao Yunbin, Zhou Shihua. Research status and prospect of DNA-based logic computing models [J]. Application Research of Computers, 2019, 36 (11): 3201-3209. )

About the Journal

  • Application Research of Computers Monthly Journal
  • Journal ID ISSN 1001-3695
    CN  51-1196/TP

Application Research of Computers, founded in 1984, is an academic journal of computing technology sponsored by Sichuan Institute of Computer Sciences under the Science and Technology Department of Sichuan Province.

Aiming at the urgently needed cutting-edge technology in this discipline, Application Research of Computers reflects the mainstream technology, hot technology and the latest development trend of computer application research at home and abroad in a timely manner. The main contents of the journal include high-level academic papers in this discipline, the latest scientific research results and major application results. The contents of the columns involve new theories of computer discipline, basic computer theory, algorithm theory research, algorithm design and analysis, blockchain technology, system software and software engineering technology, pattern recognition and artificial intelligence, architecture, advanced computing, parallel processing, database technology, computer network and communication technology, information security technology, computer image graphics and its latest hot application technology.

Application Research of Computers has many high-level readers and authors, and its readers are mainly senior and middle-level researchers and engineers engaged in the field of computer science, as well as teachers and students majoring in computer science and related majors in colleges and universities. Over the years, the total citation frequency and Web download rate of Application Research of Computers have been ranked among the top of similar academic journals in this discipline, and the academic papers published are highly popular among the readers for their novelty, academics, foresight, orientation and practicality.


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