Algorithm Research & Explore
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App. Res. of Comp. Printed Article
Vol. 37, 2020 No. 7
2041-2044

Reconstruction of gene regulatory network using parallel computational algorithm with gene expression data

Zheng Ming1a,1b
Zhou You2
Zhuo Mugui1a
1. a. Guangxi Colleges & Universities Key Laboratory of Professional Software Technology, b. Information & Electronic Engineering College, Wuzhou University, Wuzhou Guangxi 543000, China
2. College of Computer Science & Technology, Jilin University, Changchun 130012, China
DOI: 10.19734/j.issn.1001-3695.2018.12.0937

Abstract

In order to resolve the drawbacks of traditional gene network reconstruction algorithm, such as less accuracy and long running time, this paper proposed a novel algorithm. This algorithm used parallel computational algorithm with parallel computing and threshold measurement. It measured the interaction between genes by conditional mutual information. It used the CUDA and OpenMP structure based on GPU and CPU in parallel computing algorithm. Running tests on synthetic datasets demonstrate that this algorithm can handle large datasets with more accuracy and less running test than traditional algorithm, such as Bayesian model algorithm and differential equation model algorithm.

Foundation Support

国家自然科学基金资助项目(61862056,61772227)
广西自然科学基金项目面上项目(2017GXNSFAA198148)
梧州学院院级项目(2017B001)
广西高校行业软件技术重点实验室项目

Publish Information

DOI: 10.19734/j.issn.1001-3695.2018.12.0937
Publish at: Application Research of Computers Printed Article, Vol. 37, 2020 No. 7
Section: Algorithm Research & Explore
Pages: 2041-2044
Serial Number: 1001-3695(2020)07-024-2041-04

Publish History

[2020-07-05] Printed Article

Cite This Article

郑明, 周柚, 卓慕瑰. 用并行计算从基因表达数据构建大规模基因调控网络 [J]. 计算机应用研究, 2020, 37 (7): 2041-2044. (Zheng Ming, Zhou You, Zhuo Mugui. Reconstruction of gene regulatory network using parallel computational algorithm with gene expression data [J]. Application Research of Computers, 2020, 37 (7): 2041-2044. )

About the Journal

  • Application Research of Computers Monthly Journal
  • Journal ID ISSN 1001-3695
    CN  51-1196/TP

Application Research of Computers, founded in 1984, is an academic journal of computing technology sponsored by Sichuan Institute of Computer Sciences under the Science and Technology Department of Sichuan Province.

Aiming at the urgently needed cutting-edge technology in this discipline, Application Research of Computers reflects the mainstream technology, hot technology and the latest development trend of computer application research at home and abroad in a timely manner. The main contents of the journal include high-level academic papers in this discipline, the latest scientific research results and major application results. The contents of the columns involve new theories of computer discipline, basic computer theory, algorithm theory research, algorithm design and analysis, blockchain technology, system software and software engineering technology, pattern recognition and artificial intelligence, architecture, advanced computing, parallel processing, database technology, computer network and communication technology, information security technology, computer image graphics and its latest hot application technology.

Application Research of Computers has many high-level readers and authors, and its readers are mainly senior and middle-level researchers and engineers engaged in the field of computer science, as well as teachers and students majoring in computer science and related majors in colleges and universities. Over the years, the total citation frequency and Web download rate of Application Research of Computers have been ranked among the top of similar academic journals in this discipline, and the academic papers published are highly popular among the readers for their novelty, academics, foresight, orientation and practicality.

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